Description:  Uses: St. John's wort has been primarily studied for its potential antidepressant and antiviral effects. There is information to show that St. John's wort is more effective than placebo, but evidence is still lacking regarding its efficacy compared to the standard antidepressants, partially due to ineffective dosing. In addition, at least 3 studies have shown that commercially available St. John's wort products vary considerably in content and may be standardized to the wrong component (hypericin instead of hyperforin). St. John's wort is still in the early stages of clinical trials investigating its effects against certain viruses, including HIV.

Dosing: Traditional use of St. John's wort herb indicated 2 to 4 g/day doses. However, most clinical studies have been conducted on extracts, with hypericin content of 0.3% the earliest form of standardization. With the discovery of hyperforin's bioactivity, a content of 3% to 5% hyperforin has been used as a new standard. Some of the many products include LI 160(Lichtwer, 0.3% hypericin), Kira(Lichtwer, 300 mcg hypericin in 125 to 225 mg extract tablets), Hyperiforce (Bioforce, 0.33 mg hypericin in 60 mg extract/tablet), Ze 117, WS 5573 (300 mg extract, 0.5% hyperforin), WS 5572 (300 mg, 5% hyperforin), STEI 300(Steiner, 0.2% to 0.3% hypericin and 2% to 3% hyperforin), Psychotonin, Esbericum, Neuroplant, Sedariston, and Hyperforat. Doses of the extracts have ranged from 500 to 1800 mg/day.

Our Standardized St. John's Wort Extract is produced by a European quality control standards without the use of harsh chemicals. Like all European herbal extracts, the extraction of our St. John's Wort Extract is regulated to the same high standards as Over-the-Counter drugs. It is meticulously extracted to provide a standardized level of 0.3% naturally occurring hypericin. Our standardized St. John's Wort Extract contains a full spectrum of components as they occur natually in St. John's Wort. Contains to added sugar, salt, dairy, yeast, wheat, corn, soy, preservatives, artificial colors or flavors. Store in a cool, dry place and away from direct light. Quality and potency guaranteed.

Suggested Use:  As a dietary supplement, adults take one (1) capsule, one (1) to three (3) times daily with meals, or as directed by a healthcare professional.

Warnings:  Interactions: St. John's wort has been reported to decrease the efficacy of theophylline, warfarin, and digoxin and reduce AUC of indinavir (and potentially other protease inhibitors). Known interactions to cyclosporine have occurred. Concomitant use with prescription antidepressants is not recommended. Use with oral contraceptives may cause breakthrough bleeding but has not been reported to result in unexpected pregnancy.

Side Effects: Side effects are usually mild. Potential side effects include the following:Dry mouth, dizziness, constipation, other GI symptoms, and confusion. Photosensitization may also occur. In clinical trials, side effects and medication discontinuation with St. John's wort were usually less than that observed with standard antidepressants. Other possible rare side effects include induction of mania and effects on male and female reproductive capabilities.

St. John's Wort may cause increased photosensitivity in some individuals. Use caution while taking this product during exposure to sunlight. If symptoms arise, discontinue the use of this product. Consult a physiciam before using St. John's Wort with prescription antidepressants.

Keep out of reach of children. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Serving Size:  1 Capsule